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Tax incentives, credits, and programs from the Commonwealth of Pennsylvania

Pittsburgh’s life sciences sector continues to grow rapidly, with support from a range of statewide incentives that reduce costs and accelerate innovation.

The Research & Development (R&D) Tax Credit allows companies to offset a portion of their qualified R&D expenses against tax liabilities, providing critical funding to reinvest in scientific and clinical progress. Importantly, early-stage life sciences companies that are not yet profitable can sell or transfer these credits, enabling access to immediate working capital to advance their pipelines.

The Keystone Innovation Zone (KIZ) Tax Credit targets companies located within designated innovation zones such as Pittsburgh’s South Oakland. Life sciences firms that are less than eight years old can receive up to $100,000 annually in tax credits, supporting operational growth during the crucial early stages of commercialization.

The Ben Franklin Technology Partners (BFTP) program supports early-stage company funding in the form of grants, loans, or equity investments, alongside expert mentorship and strategic connections to industry and investor networks. This combination of capital and guidance has helped numerous Pittsburgh biotech and medtech companies scale from research concept to market-ready solution.

The PA First program provides funding to support infrastructure, building improvements, and equipment purchases – a critical resource for companies expanding lab or manufacturing capacity.

WEDnetPA offers training reimbursements to employers, ensuring the state’s workforce remains highly skilled and aligned with the demands of modern life sciences research and production.

These programs collectively strengthen Pittsburgh’s position as a leading life sciences hub, empowering companies to innovate, grow, and improve health outcomes while creating high-quality jobs throughout the region.

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